I've watched Saturday Night Live for well over 30 years now, meaning that I've seen pretty much every episode ever, and I thought Zach Galifianakis' opening monologue this past weekend was one of the funniest I can remember. Most of it was his stand-up bit, but by the end he'd stripped to an Annie outfit and lip-synced to the song "Tomorrow" while tearing messages off an easel and I was literally laughing outloud. This guy is just genuinely hilarious to me. He played some other funnies characters during the whole but I thought the monologue set the tone perfectly.
Here's the whole bit: